Producers try to evade these authorized limitations by substituting different chemical substances in their mixtures, although the DEA carries on to watch and update the listing of banned cannabinoid derivatives.1Artificial cannabinoids like Spice tend to be marketed as “lawful” choices to marijuana, but they are not totally exempt from regulati
) use. We report 2 individuals with no prior heritage of neurological disorder that expert their to start with generalized tonic–clonic seizure right after smoking Spice. The system powering the feasible proconvulsant outcome of synthetic cannabinoids is not really acknowledged, but it may be due to their effects on the cannabinoid receptor CB1.
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